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Orientation sessions May 3, 6, 10, 13, 17, 20, 24, 27, 31, 2024


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New publications: Natalya Kurochkina. Protein Structure and Modeling

Book Link
New publications: Phosphorylation, Dephosphorylation, and Multiprotein Assemblies Regulate Dynamic Behavior of Neuronal Cytoskeleton: A Mini-Review Natalya Kurochkina* , Manju Bhaskar, ShadraPrasad Yadav and Harish Pant* Mini Review, Front. Mol. Neurosci in press. .Collaboration: The School of Theoretical Modeling and NIH

Link to Pubmed
New publications: Hall BE, Prochazkova M, Sapio MR, Minetos P, Kurochkina N, Binukumar BK, Amin ND, Terse A, Joseph J, Raithel SJ, Mannes AJ, Pant HC, Chung MK, Iadarola MJ, Kulkarni AB. Phosphorylation of the Transient Receptor Potential Ankyrin 1 by Cyclin-dependent Kinase 5 affects Chemo-nociception. Sci Rep. 2018 Jan 19;8(1):1177. doi: 10.1038/s41598-018-19532-6. PubMed PMID: 29352128; PubMed Central PMCID: PMC5775258.Collaboration: The School of Theoretical Modeling and NIH
Link to Pubmed

New publications: http://www.springer.com/us/book/9783319200972 Congratulations to Authors and Springer with a year anniversary of our book: 11 Chapters. 18 Authors. More than a year of work. Thank you all.Link to Book Home Page

New publications: Helical Assemblies: Structure Determinants. Journalof Theoretical Biology.Collaboration: The School of Theoretical Modeling and Clinical Center/NIHLink to Pubmed
Workshops and Webinars
Helical Assemblies.
Protein Modeling/Structure determination. Candidate proteins.
May 3, 6, 10, 13, 17, 20, 24, 27, 31, 2024
3 - 4 pm ET
Interested in the structure of these and other proteins?
Sign for the Workshops/Webinars
3 - 4 pm ET

Workshop and Webinar Resistration
Recent Models
Does your protein bind calmodulin? Submit amino acid sequence to find out.

Protein Models. Protein Modeling
Webinars Tools



COLLABORATIONS 

Department of Biophysics

National Institutes of Health/NHGRI

Mutations in Uridine diphosphate N-Acetylglucoseamine 2-epimerase/N-acetylmannoseamine kinase involved in hereditary inclusion body myopathy (HIBM)

Link to list of top manuscripts in the domain

The American Red Cross Laboratory Holland Laboratory

Conformational Changes in Fibrin/Fibrinogen

Department of Mathematics, Statistics, Algorithm Design and Programming

CGH Technologies/FAA


Clinical Center/NIH
Phosphorylation of the Transient Receptor Potential Ankyrin 1 by Cyclin-dependent Kinase 5 affects Chemo-nociception. Sci Rep. 2018 Jan 19;8(1):1177. doi: 10.1038/s41598-018-19532-6.

GRADUATE PROGRAM  BIOMEDICAL RESEARCH/BIOCHEMISTRY/ORGANIC CHEMISTRY  SCIENCE WRITING  BIOSTATISTICS

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COURSES FOR PROFESSIONAL DEVELOPMENT   PROTEIN MODELING   BIOSTATISTICS  BIOCHEMISTRY  BIOINFORMATICS

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SEMESTER AND SUMMER COURSES

MATHEMATICS                    STATISTICS                           CALCULUS

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BIOCHEMISTRY                   PROTEIN CHEMISTRY        PROTEIN MODELING

PHOTOSYNTHESIS AND RESPIRATION

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ADVANCED COURSES FOR MIDDLE and HIGH SCHOOL STUDENTS INTERESTED IN MATH AND SCIENCE

MATHEMATICS                    CALCULUS                            PHYSICS

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Welcome to www.schtm.org



Welcome to www.schtm.org



Welcome to www.schtm.org



Teachers CertificationGraduate ProgramDocument
Webinar: Candidate Proteins
Why Take a CourseProtein ModelsProtein Modeling Tools
Organizer: Biographical Sketch

WEBINAR REGISTRATION

Webinar (no charge):
Candidate Proteins.

Is your protein an important target?
Tell us why.





COURSE REGISTRATION

Courses
Semester course - $1,400
One Day Course - $450.00
Model yourself - $12.50

Payment*Course Selection



WORKSHOP REGISTRATION

Workshop
Cost: $1,400

Payment*Workshop

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Daytime Phone() -
Evening Phone() -
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Last Name
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Address Line 2
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Daytime Phone() -
Evening Phone() -
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Comments
  Submit your sequence
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Amino Acid Sequence
Comments
 

     PROTEIN MODELING  ONE DAY COURSE


 9:30-10:00   Organizing procedures

     Introduction of all participants

     Short introduction to the topics of the course

10-10:55

 

Protein conformation

     Parameters characterizing polypeptide chain

     Topology, orientation of protein secondary structure elements

 

11-11:55

 

New mathematical approaches to protein structure prediction/protein modeling

     Formula for spatial location of amino acid residues within secondary structure

     elements

     Application to the prediction of protein structure

     Algorithms

 

12-1:00

 

     Lunch

 

1-1:55

 

Description of helix-helix interfaces, active sites

     Structure comparison

     Specific side chain interactions

     Amino acid composition of helix-helix interfaces

     Variations among homologs and mutagenesis

     Disulfide bonds

Representing molecular forces affecting protein folding

Modeling of loops

Protein - nucleic acid interactions

 

2-2:55

 

Agonist/antagonist affects on binding sites

Conformational changes

Formation of channels

 

3-3:55

 

Application of modeling to the analysis of the protein families involved in desease pathogenesis

 

4-4:30

 

Organizing procedures

     Summarizing questions

     Concluding remarks

 

Course is supplemented by a text book and CD with examples

Course participants are welcome to suggest topics of individual (group) interest during registration (For each session or following course discussions and practical applications)  

 
 
 

Recent Models

Document
Protein Models: ACE and Calmodulin

Protein Modeling

Protein modeling is a set of methods to model the structure of a protein or protein complex. Protein modeling is an essential part of Biophysics, Biochemistry, Structural Biology, Biomedical research, and other disciplines that study protein function.

Theoretical Modeling

A theoretical model is a framework that researchers use to structure a study process and plan how to approach a specific research inquiry. It can allow you to define the purpose of your research and develop an informed perspective.

Biophysics

applies principles of physics to studies of living organisms.

Biochemistry

applies principles of chemistry to studies of living organisms.